As I stirred melted butter and fragrant garlic in the skillet, a wave of nostalgia washed over me, reminding me of family dinners that lingered well into the night. Today, I’m excited to share my Garlic Butter Shrimp Scampi Lasagna—an exquisite fusion of comfort food and seafood that transforms any meal into a celebration. The creamy layers, perfectly cooked shrimp, and melted cheese create a delightful harmony that’s both indulgent and satisfying. Plus, this dish is surprisingly quick to prepare, making it an effortless option for busy weeknights or special gatherings. Trust me, this creamy shrimp lasagna will have everyone asking for seconds! Are you ready to dive into this culinary adventure?

Why is Garlic Butter Shrimp Scampi Lasagna Special?

Irresistible Layers: Each bite of this lasagna is a delightful journey through layers of creamy garlic butter, succulent shrimp, and melted cheese.
Quick Preparation: You won’t spend hours in the kitchen; this recipe is designed for ease without sacrificing flavor.
Versatile Ingredients: Feel free to substitute shrimp with other seafood or even add in some veggies for a personalized twist!
Crowd-Pleasing Appeal: Whether for a family dinner or a gathering with friends, this dish will surely impress your guests, just like my Honey Butter Chicken.
Comfort and Luxury: It combines the heartwarming comfort of traditional lasagna with luxurious seafood flavors, making it a unique dish that stands out on any table.

Garlic Butter Shrimp Scampi Lasagna Ingredients

  • For the Creamy Sauce

  • Butter – Adds richness and flavor to the sauce.
    Substitution Note: Can use olive oil for a lighter option.

  • Garlic – Provides aromatic depth and enhances flavor.
    Prep Note: Use fresh garlic for the best taste.

  • Heavy Cream – Creates a rich, creamy sauce.
    Substitution Note: Use half-and-half or a milk-butter combo for a lighter version.

  • Chicken Broth – Enhances overall flavor of the sauce.
    Prep Note: Low-sodium broth recommended to control saltiness.

  • Lemon Zest & Juice – Brightens flavors and cuts through richness.
    Substitution Note: Lime juice can be used for a different citrus touch.

  • Salt and Black Pepper – Essential for seasoning.
    Note: Adjust to taste.

  • Crushed Red Pepper Flakes – Adds a hint of heat to balance the richness.
    Optional Note: Adjust quantity based on desired spice level.

  • For the Shrimp

  • Large Shrimp – Main protein and source of seafood flavor.
    Substitution Note: Can swap with scallops or crab meat; adjust cooking times accordingly.

  • For the Lasagna Layering

  • Lasagna Noodles – Structure of the dish.
    Prep Note: Pre-cook according to package instructions.

  • Ricotta Cheese – Adds creaminess and structure to each layer.
    Substitution Note: Cottage cheese can be used as a lighter alternative.

  • Shredded Mozzarella Cheese – Melting quality that binds the layers together.
    Prep Note: Use fresh mozzarella for improved taste.

  • Grated Parmesan Cheese – Adds savory depth and a slightly salty flavor.
    Note: Can substitute with Pecorino Romano for a sharper taste.

  • Chopped Fresh Parsley – For garnish and added freshness.
    Optional Note: Swap for basil or chives for different flavors.

  • Olive Oil – For greasing the baking dish.
    Substitution Note: Any cooking oil can be used.

This Garlic Butter Shrimp Scampi Lasagna recipe is not just delicious; it’s a delightful way to bring family and friends together at the dinner table. Enjoy this creamy masterpiece!

Step‑by‑Step Instructions for Garlic Butter Shrimp Scampi Lasagna

Step 1: Prepare Garlic Shrimp
In a large skillet, melt 4 tablespoons of butter over medium heat until bubbly. Add 3 minced garlic cloves and sauté until fragrant, about 1 minute. Toss in 1 pound of large shrimp and sprinkle with ½ teaspoon crushed red pepper flakes. Cook until the shrimp turn pink and opaque, roughly 3-4 minutes, then transfer to a plate and set aside.

Step 2: Make Cream Sauce
In the same skillet, pour in 1 cup of heavy cream and 1 cup of chicken broth, stirring well to combine. Add the juice and zest of 1 lemon, seasoning with salt and black pepper to taste. Bring the mixture to a gentle simmer over medium heat and cook for about 5-7 minutes, stirring occasionally until the sauce thickens.

Step 3: Combine Cheeses
Remove the skillet from heat and stir in 1 cup of ricotta cheese until well combined. Then, add 2 cups of shredded mozzarella cheese and ½ cup of grated Parmesan cheese, mixing until the cheeses melt into the creamy sauce. Return the shrimp to the skillet and gently fold everything together, ensuring the shrimp are well-coated in the garlic butter sauce.

Step 4: Layer Lasagna
Preheat your oven to 375°F (190°C). Grease a 9×13 inch baking dish with a drizzle of olive oil. Start by spreading a layer of the garlic butter shrimp scampi sauce on the bottom. Layer cooked lasagna noodles over the sauce, followed by more sauce, and sprinkle additional mozzarella. Repeat the layers until all ingredients are used, finishing with a generous layer of mozzarella cheese on top.

Step 5: Bake
Cover the baking dish with aluminum foil and bake for 25 minutes. After that, remove the foil and bake for an additional 10-15 minutes, or until the top is golden and bubbly. Allow the garlic butter shrimp scampi lasagna to cool for about 10 minutes before serving; this will help the layers set and make it easier to cut. Garnish with chopped fresh parsley for a pop of color and freshness.

Make Ahead Options

These Garlic Butter Shrimp Scampi Lasagna are perfect for meal prep enthusiasts! You can prepare the entire lasagna up to 24 hours in advance, allowing for an easy weeknight dinner. Simply assemble the layers, cover tightly with plastic wrap, and refrigerate until it’s time to bake. To maintain the creamy texture, ensure that the sauce is still warm when layering, preventing the noodles from soaking up too much moisture. When ready to serve, preheat your oven and bake from the refrigerator, adding 5-10 minutes to the baking time. Trust me, you’ll enjoy restaurant-quality results with minimal effort!

Expert Tips for Garlic Butter Shrimp Scampi Lasagna

  • Perfect Layering: Make sure your lasagna noodles slightly overlap when layering. This ensures stability and prevents the dish from falling apart when served.

  • Prevent Soggy Bottoms: Layer the sauce carefully, and avoid too much liquid at the bottom to prevent soggy noodles. Letting the dish cool slightly before serving helps with structure.

  • Timing is Key: Always adjust the baking time if you prepare the garlic butter shrimp scampi lasagna ahead of time; chilled ingredients may require an extra 10-15 minutes in the oven.

  • Fresh Ingredients Matter: Use fresh garlic and quality shrimp for the best flavor. Frozen shrimp can work, but ensure they’re fully thawed and well-drained.

  • Cheese Choices: Opt for whole milk ricotta and fresh mozzarella cheese for creaminess and superior melting quality. This makes a significant difference in the overall taste of your lasagna.

  • Heat Adjustments: Customize the spice level by adjusting crushed red pepper flakes according to your taste. Don’t overwhelm the dish; it should enhance—not overshadow—the rich flavors of the creamy sauce.

How to Store and Freeze Garlic Butter Shrimp Scampi Lasagna

Fridge: Store leftover garlic butter shrimp scampi lasagna in an airtight container for up to 3 days. Reheat individual portions in the microwave or oven until bubbly.

Freezer: For longer storage, tightly wrap the lasagna in plastic wrap and aluminum foil before freezing. It can be stored for up to 3 months. Thaw overnight in the fridge before reheating.

Reheating: Reheat the lasagna in the oven at 350°F (175°C) for about 20-25 minutes, covered with foil to prevent drying out.

Pre-baking Tip: If preparing in advance, consider assembling the dish but do not bake until you’re ready to serve. This keeps the flavors fresh and vibrant in your garlic butter shrimp scampi lasagna.

What to Serve with Garlic Butter Shrimp Scampi Lasagna?

Indulging in a dish as rich as this is an experience in itself, and pairing it correctly can elevate the meal to new heights.

  • Garlic Bread: The perfect crunchy side that can soak up any leftover sauce, complementing the flavors of the lasagna beautifully.

  • Classic Caesar Salad: Crisp romaine, creamy dressing, and crunchy croutons provide a refreshing balance to the rich lasagna.

  • Roasted Asparagus: Tender and slightly charred, this green veggie adds a touch of elegance and a vibrant color to the table.

  • Crispy Fried Zucchini: Lightly breaded and fried, these bites bring a delightful crunch, enhancing the dish’s creamy profile.

  • Herbed Quinoa: A nutritious alternative with a nutty flavor, this side offers a wholesome contrast to the indulgent lasagna layers.

  • White Wine Spritzer: A refreshing drink with subtle bubbles and a hint of citrus perfectly complements the savory seafood flavors in the lasagna.

  • Lemon Sorbet: This light, refreshing dessert cleanses the palate after the rich meal, leaving you feeling satisfied yet unburdened.

  • Caprese Skewers: Simple yet flavorful, fresh tomatoes, basil, and mozzarella drizzled with balsamic glaze create a fresh and inviting starter.

  • Grilled Garlic Shrimp: For the seafood enthusiasts, grilling some shrimp adds another layer of flavor, harmoniously echoing the sweet and savory notes of the lasagna.

  • Berry Tart: A vibrant dessert that combines sweetness and acidity, it wraps up the meal on a delightful note, balancing the rich lasagna’s heaviness.

Garlic Butter Shrimp Scampi Lasagna Variations

Feel free to get creative with this recipe; there’s an abundance of delightful twists waiting for you!

  • Dairy-Free: Use coconut milk instead of heavy cream for a creamy, plant-based alternative that still tastes amazing.
    If you’re looking for a lighter version, you can also consider trying nut-based cheeses for the ricotta and mozzarella layers.

  • Seafood Swap: Replace shrimp with lobster or crab for an upscale version that adds a touch of luxury to this already glorious dish.
    Just keep an eye on cooking times, as lobster cooks faster than shrimp.

  • Gluten-Free Noodles: Opt for gluten-free lasagna sheets if you’re catering to dietary restrictions without sacrificing taste.
    There are fantastic varieties available made from rice or corn that hold up beautifully in the layers.

  • Zesty Twist: Add capers or olives for a briny, savory kick that brightens the overall flavor of the lasagna.
    They pair so well with the garlic butter sauce, enhancing the taste of the dish and taking it to the next level.

  • Veggie Boost: Toss in spinach or sautéed mushrooms to up the nutritional value while adding vibrant colors and textures.
    These fantastic additions make this dish more exciting and healthy, balancing out the richness.

  • Spicy Kick: Amp up the heat with sliced jalapeños or a splash of your favorite hot sauce for a piquant finish.
    This can be a great way to cater to heat lovers at your table; just be sure to tailor the amount to your crowd!

  • Creamy Alternative: Trade out half the heavy cream for sour cream or Greek yogurt to introduce a slight tanginess that complements the shrimp beautifully.
    This upgrade not only makes the sauce extra rich but also adds a lovely depth of flavor.

  • Herb Infusion: Swap parsley for fresh basil or dill for an aromatic twist that adds freshness and enhances the dish’s coastal vibes.
    These herbs infuse the lasagna with delightful scents that evoke memories of seaside dining, perfect for gatherings.

With these variations, you can make each rendition of garlic butter shrimp scampi lasagna uniquely yours! Be sure to check out our other delicious dishes, like Garlic Butter Salmon and Garlic Naan Bread, for more inspiration.

Garlic Butter Shrimp Scampi Lasagna Recipe FAQs

What type of shrimp should I use for this recipe?
Absolutely! Use large shrimp for the best seafood flavor, but you can also substitute with scallops or crab meat. Just remember to adjust the cooking times accordingly, as scallops may take slightly longer to cook.

How should I store leftover garlic butter shrimp scampi lasagna?
For fridge storage, keep your leftover lasagna in an airtight container for up to 3 days. Reheating individual portions can be done in the microwave or oven until heated through and bubbly.

Can I freeze garlic butter shrimp scampi lasagna?
Very! This dish is freezer-friendly. Wrap the lasagna tightly in plastic wrap and then in aluminum foil before freezing. It will save well for up to 3 months. To enjoy, thaw it overnight in the refrigerator before reheating.

How do I reheat frozen lasagna without losing flavor?
To maintain taste, reheat your frozen garlic butter shrimp scampi lasagna in the oven at 350°F (175°C) for approximately 20-25 minutes, covered with foil. This method helps prevent it from drying out while ensuring it heats evenly.

What if my lasagna noodles are too soft?
If your noodles become too soft, they may break when layered. I recommend slightly undercooking them while boiling, making sure they are al dente. This way, they’ll hold their shape better during baking.

Are there any dietary considerations for pets or allergies with this recipe?
Yes! Be cautious if you have shellfish allergies, as shrimp is the primary protein in this dish. Additionally, if you have pets, avoid sharing leftovers that contain shrimp and dairy, as these can be harmful to certain animals. Always consult your veterinarian if unsure.

Garlic Butter Shrimp Scampi Lasagna

Garlic Butter Shrimp Scampi Lasagna: Creamy Comfort Awaits

Indulge in this Garlic Butter Shrimp Scampi Lasagna, a creamy fusion of comfort food and seafood that's perfect for any occasion.
Prep Time 20 minutes
Cook Time 50 minutes
Cooling Time 10 minutes
Total Time 1 hour 20 minutes
Servings: 6 slices
Course: Dinner
Cuisine: Italian
Calories: 520

Ingredients
  

For the Creamy Sauce
  • 4 tablespoons Butter Can use olive oil for a lighter option.
  • 3 cloves Garlic Use fresh garlic for the best taste.
  • 1 cup Heavy Cream Use half-and-half or a milk-butter combo for a lighter version.
  • 1 cup Chicken Broth Low-sodium broth recommended to control saltiness.
  • 1 whole Lemon Zest & Juice Lime juice can be used for a different citrus touch.
  • 1 teaspoon Salt Adjust to taste.
  • 1/2 teaspoon Black Pepper Adjust to taste.
  • 1/2 teaspoon Crushed Red Pepper Flakes Adjust quantity based on desired spice level.
For the Shrimp
  • 1 pound Large Shrimp Can swap with scallops or crab meat; adjust cooking times accordingly.
For the Lasagna Layering
  • 9 sheets Lasagna Noodles Pre-cook according to package instructions.
  • 1 cup Ricotta Cheese Cottage cheese can be used as a lighter alternative.
  • 2 cups Shredded Mozzarella Cheese Use fresh mozzarella for improved taste.
  • 1/2 cup Grated Parmesan Cheese Can substitute with Pecorino Romano for a sharper taste.
  • 1/4 cup Chopped Fresh Parsley Swap for basil or chives for different flavors.
  • 1 tablespoon Olive Oil Any cooking oil can be used.

Equipment

  • Large Skillet
  • 9x13-inch baking dish

Method
 

Step-by-Step Instructions for Garlic Butter Shrimp Scampi Lasagna
  1. In a large skillet, melt 4 tablespoons of butter over medium heat until bubbly. Add 3 minced garlic cloves and sauté until fragrant, about 1 minute. Toss in 1 pound of large shrimp and sprinkle with ½ teaspoon crushed red pepper flakes. Cook until the shrimp turn pink and opaque, roughly 3-4 minutes, then transfer to a plate and set aside.
  2. In the same skillet, pour in 1 cup of heavy cream and 1 cup of chicken broth, stirring well to combine. Add the juice and zest of 1 lemon, seasoning with salt and black pepper to taste. Bring the mixture to a gentle simmer over medium heat and cook for about 5-7 minutes, stirring occasionally until the sauce thickens.
  3. Remove the skillet from heat and stir in 1 cup of ricotta cheese until well combined. Then, add 2 cups of shredded mozzarella cheese and ½ cup of grated Parmesan cheese, mixing until the cheeses melt into the creamy sauce. Return the shrimp to the skillet and gently fold everything together, ensuring the shrimp are well-coated in the garlic butter sauce.
  4. Preheat your oven to 375°F (190°C). Grease a 9x13 inch baking dish with a drizzle of olive oil. Start by spreading a layer of the garlic butter shrimp scampi sauce on the bottom. Layer cooked lasagna noodles over the sauce, followed by more sauce, and sprinkle additional mozzarella. Repeat the layers until all ingredients are used, finishing with a generous layer of mozzarella cheese on top.
  5. Cover the baking dish with aluminum foil and bake for 25 minutes. After that, remove the foil and bake for an additional 10-15 minutes, or until the top is golden and bubbly. Allow the garlic butter shrimp scampi lasagna to cool for about 10 minutes before serving; this will help the layers set and make it easier to cut. Garnish with chopped fresh parsley for a pop of color and freshness.

Nutrition

Serving: 1sliceCalories: 520kcalCarbohydrates: 45gProtein: 25gFat: 30gSaturated Fat: 18gPolyunsaturated Fat: 3gMonounsaturated Fat: 5gCholesterol: 250mgSodium: 800mgPotassium: 500mgFiber: 2gSugar: 3gVitamin A: 700IUVitamin C: 8mgCalcium: 300mgIron: 2mg

Notes

This Garlic Butter Shrimp Scampi Lasagna recipe is a delightful way to bring family and friends together at the dinner table.

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